Entry Detail



General Information

Database ID:BRCA29822
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:PROK2
Full Name:prokineticin 2
Category:mRNA
Synonyms:BV8|HH4|KAL4|MIT1|PK2
Chromosome:chr3
Strand:-
Coordinate:
Start Site(bp):71771656End Site(bp):71785206
Gene Summary:This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000163421
HGNC ID:HGNC:18455
Entrez Gene:60675



Expression Profile of PROK2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-101-3p
YES
YES
YES
hsa-miR-1271-5p
YES
YES
YES
hsa-miR-144-3p
YES
YES
NO
hsa-miR-182-5p
YES
YES
NO
hsa-miR-200b-3p
YES
YES
NO
hsa-miR-200c-3p
YES
YES
NO
hsa-miR-23a-3p
YES
YES
YES
hsa-miR-23b-3p
YES
YES
YES
hsa-miR-335-5p
YES
YES
NO
hsa-miR-365a-3p
YES
YES
NO
hsa-miR-429
YES
YES
NO
hsa-miR-499a-5p
YES
YES
NO
hsa-miR-96-5p
YES
YES
YES
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