ctcRbase

Entry Detail

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General Information

Database ID: BRCA29900 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: LRP8 Full Name: LDL receptor related protein 8 Category: mRNA Synonyms: APOER2|HSZ75190|LRP-8|MCI1 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 53242364 End Site(bp): 53328070 Gene Summary: This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2011] External Links: Ensembl ID: ENSG00000157193 HGNC ID: HGNC:6700 Entrez Gene: 7804

Expression Profile of LRP8 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-137 YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-32-5p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-330-3p YES NO YES hsa-miR-342-3p YES NO YES hsa-miR-362-3p YES NO NO hsa-miR-363-3p YES YES NO hsa-miR-365a-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-374a-5p YES YES NO hsa-miR-374b-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-409-5p YES NO YES hsa-miR-454-3p YES YES YES hsa-miR-455-5p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-543 YES YES NO hsa-miR-613 YES YES NO hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO hsa-miR-93-5p YES YES NO Display: