ctcRbase

Entry Detail

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General Information

Database ID: BRCA29959 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MSX2 Full Name: msh homeobox 2 Category: mRNA Synonyms: CRS2|FPP|HOX8|MSH|PFM|PFM1 Chromosome: chr5 Strand: + Coordinate: Start Site(bp): 174724533 End Site(bp): 174730893 Gene Summary: This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000120149 HGNC ID: HGNC:7392 Entrez Gene: 4488

Expression Profile of MSX2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-128-3p YES YES NO hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-216b-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-375 YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-599 YES YES NO Display: