ctcRbase

Entry Detail

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General Information

Database ID: BRCA30061 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: HTRA1 Full Name: HtrA serine peptidase 1 Category: mRNA Synonyms: ARMD7|CADASIL2|CARASIL|HtrA|L56|ORF480|PRSS11 Chromosome: chr10 Strand: + Coordinate: Start Site(bp): 122461525 End Site(bp): 122514908 Gene Summary: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000166033 HGNC ID: HGNC:9476 Entrez Gene: 5654

Expression Profile of HTRA1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-149-5p YES YES NO hsa-miR-150-5p YES YES NO hsa-miR-183-5p YES YES NO hsa-miR-217 YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-33a-5p YES YES NO hsa-miR-33b-5p YES YES NO hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-376c-3p YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-494-3p YES YES YES hsa-miR-495-3p YES YES NO Display: