ctcRbase

Entry Detail

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General Information

Database ID: BRCA30186 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: LMAN2L Full Name: lectin, mannose binding 2 like Category: mRNA Synonyms: MRT52|VIPL Chromosome: chr2 Strand: - Coordinate: Start Site(bp): 96705929 End Site(bp): 96740064 Gene Summary: This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway. [provided by RefSeq, Apr 2016] External Links: Ensembl ID: ENSG00000114988 HGNC ID: HGNC:19263 Entrez Gene: 81562

Expression Profile of LMAN2L Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES NO hsa-miR-107 YES YES NO hsa-miR-124-3p YES YES YES hsa-miR-15a-5p YES YES YES hsa-miR-15b-5p YES YES YES hsa-miR-16-5p YES YES YES hsa-miR-195-5p YES YES YES hsa-miR-296-3p YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-424-5p YES YES YES hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-486-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-490-3p YES YES NO hsa-miR-497-5p YES YES YES hsa-miR-506-3p YES YES NO hsa-miR-542-3p YES YES NO hsa-miR-874-3p YES YES NO hsa-miR-875-5p YES YES NO Display: