Entry Detail



General Information

Database ID:BRCA30233
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:RAPGEF1
Full Name:Rap guanine nucleotide exchange factor 1
Category:mRNA
Synonyms:C3G|GRF2
Chromosome:chr9
Strand:-
Coordinate:
Start Site(bp):131576770End Site(bp):131740074
Gene Summary:This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000107263
HGNC ID:HGNC:4568
Entrez Gene:2889



Expression Profile of RAPGEF1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-106a-5p
YES
NO
YES
hsa-miR-106b-5p
YES
NO
YES
hsa-miR-124-3p
YES
YES
YES
hsa-miR-142-5p
YES
NO
YES
hsa-miR-15a-5p
YES
NO
YES
hsa-miR-15b-5p
YES
NO
YES
hsa-miR-16-5p
YES
NO
YES
hsa-miR-17-5p
YES
NO
YES
hsa-miR-185-5p
YES
NO
NO
hsa-miR-195-5p
YES
NO
YES
hsa-miR-200b-3p
YES
YES
YES
hsa-miR-200c-3p
YES
YES
YES
hsa-miR-20a-5p
YES
NO
YES
hsa-miR-20b-5p
YES
NO
YES
hsa-miR-219a-5p
YES
NO
YES
hsa-miR-329-3p
YES
YES
NO
hsa-miR-346
YES
NO
YES
hsa-miR-370-3p
YES
YES
NO
hsa-miR-377-3p
YES
YES
NO
hsa-miR-421
YES
YES
NO
hsa-miR-424-5p
YES
NO
YES
hsa-miR-429
YES
YES
YES
hsa-miR-452-5p
YES
NO
YES
hsa-miR-495-3p
YES
YES
YES
hsa-miR-497-5p
YES
NO
YES
hsa-miR-503-5p
YES
YES
NO
hsa-miR-506-3p
YES
YES
NO
hsa-miR-519d-3p
YES
NO
YES
hsa-miR-93-5p
YES
NO
YES
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