| ncRNA Symbol: | AP3B2 |
| Full Name: | adaptor related protein complex 3 subunit beta 2 |
| Category: | mRNA |
| Synonyms: | EIEE48|NAPTB |
| Chromosome: | chr15 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 82659281 | End Site(bp): | 82709914 |
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| Gene Summary: | Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017] |
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