| ncRNA Symbol: | DPYSL2 |
| Full Name: | dihydropyrimidinase like 2 |
| Category: | mRNA |
| Synonyms: | CRMP-2|CRMP2|DHPRP2|DRP-2|DRP2|N2A3|ULIP-2|ULIP2 |
| Chromosome: | chr8 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 26514022 | End Site(bp): | 26658178 | |
| Gene Summary: | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |
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