ctcRbase

Entry Detail

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General Information

Database ID: BRCA31132 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CELSR1 Full Name: cadherin EGF LAG seven-pass G-type receptor 1 Category: mRNA Synonyms: ADGRC1|CDHF9|FMI2|HFMI2|ME2 Chromosome: chr22 Strand: - Coordinate: Start Site(bp): 46360834 End Site(bp): 46537170 Gene Summary: The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000075275 HGNC ID: HGNC:1850 Entrez Gene: 9620

Expression Profile of CELSR1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-1271-5p YES NO YES hsa-miR-129-5p YES NO YES hsa-miR-1297 YES YES YES hsa-miR-142-5p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-182-5p YES NO YES hsa-miR-194-5p YES YES YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-19a-3p YES NO YES hsa-miR-19b-3p YES NO YES hsa-miR-208a-3p YES NO YES hsa-miR-208b-3p YES NO YES hsa-miR-216b-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-26a-5p YES YES YES hsa-miR-26b-5p YES YES YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-451a YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-499a-5p YES NO YES hsa-miR-505-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-96-5p YES NO YES Display: