Entry Detail



General Information

Database ID:BRCA31211
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:APBA1
Full Name:amyloid beta precursor protein binding family A member 1
Category:mRNA
Synonyms:D9S411E|LIN10|MINT1|X11|X11A|X11ALPHA
Chromosome:chr9
Strand:-
Coordinate:
Start Site(bp):69427530End Site(bp):69672306
Gene Summary:The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]
External Links:
Ensembl ID:ENSG00000107282
HGNC ID:HGNC:578
Entrez Gene:320



Expression Profile of APBA1 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-103a-3p
YES
NO
YES
hsa-miR-107
YES
NO
YES
hsa-miR-149-5p
NO
YES
YES
hsa-miR-181a-5p
NO
YES
YES
hsa-miR-181b-5p
NO
YES
YES
hsa-miR-181c-5p
NO
YES
YES
hsa-miR-181d-5p
NO
YES
YES
hsa-miR-185-5p
YES
YES
NO
hsa-miR-24-3p
NO
YES
YES
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