Entry Detail



General Information

Database ID:BRCA31269
Cancer Type:breast cancer
Dataset:GSE55807
CTCs/CTM Isolation Method:CTC-iChip



Gene Information

ncRNA Symbol:PRRG2
Full Name:proline rich and Gla domain 2
Category:mRNA
Synonyms:PRGP2
Chromosome:chr19
Strand:+
Coordinate:
Start Site(bp):49580646End Site(bp):49591015
Gene Summary:The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
External Links:
Ensembl ID:ENSG00000126460
HGNC ID:HGNC:9470
Entrez Gene:5639



Expression Profile of PRRG2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:NA
Display:N/A