ctcRbase

Entry Detail

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General Information

Database ID: BRCA31774 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: H2AFX Full Name: H2A histone family member X Category: mRNA Synonyms: H2A.X|H2A/X|H2AX Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 119093854 End Site(bp): 119095467 Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015] External Links: Ensembl ID: ENSG00000188486 HGNC ID: HGNC:4739 Entrez Gene: 3014

Expression Profile of H2AFX Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-138-5p YES NO YES hsa-miR-145-5p YES YES YES hsa-miR-22-3p YES NO YES hsa-miR-24-3p YES YES YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-328-3p YES YES YES hsa-miR-455-3p YES NO YES hsa-miR-455-5p YES YES NO hsa-miR-488-3p YES YES NO Display: