| ncRNA Symbol: | HLF | | Full Name: | HLF, PAR bZIP transcription factor | | Category: | mRNA | | Synonyms: | - | | Chromosome: | chr17 | | Strand: | + | | Coordinate: | | Start Site(bp): | 55265012 | End Site(bp): | 55325065 | | | Gene Summary: | This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] | | External Links: | |
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