ctcRbase

Entry Detail

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General Information

Database ID: BRCA33163 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: NECTIN1 Full Name: nectin cell adhesion molecule 1 Category: mRNA Synonyms: CD111|CLPED1|ED4|HIgR|HV1S|HVEC|OFC7|PRR|PRR1|PVRL1|PVRR|PVRR1|SK-12|nectin-1 Chromosome: chr11 Strand: - Coordinate: Start Site(bp): 119623408 End Site(bp): 119729084 Gene Summary: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009] External Links: Ensembl ID: ENSG00000110400 HGNC ID: HGNC:9706 Entrez Gene: 5818

Expression Profile of NECTIN1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO YES hsa-miR-107 YES NO YES hsa-miR-1271-5p YES NO YES hsa-miR-135a-5p YES NO YES hsa-miR-135b-5p YES NO YES hsa-miR-145-5p YES NO YES hsa-miR-147a YES NO NO hsa-miR-148a-3p YES NO YES hsa-miR-148b-3p YES NO YES hsa-miR-149-5p YES NO YES hsa-miR-152-3p YES NO YES hsa-miR-15a-5p YES NO YES hsa-miR-15b-5p YES NO YES hsa-miR-16-5p YES NO YES hsa-miR-195-5p YES NO YES hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-200b-3p YES NO YES hsa-miR-200c-3p YES NO YES hsa-miR-214-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-300 YES YES YES hsa-miR-34a-5p YES NO YES hsa-miR-34c-5p YES NO YES hsa-miR-381-3p YES YES YES hsa-miR-423-5p YES NO NO hsa-miR-424-5p YES NO YES hsa-miR-429 YES NO YES hsa-miR-449a YES NO YES hsa-miR-449b-5p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-497-5p YES NO YES hsa-miR-503-5p YES NO YES hsa-miR-520f-3p YES NO YES hsa-miR-625-5p YES NO NO hsa-miR-665 YES NO YES hsa-miR-96-5p YES NO YES Display: