ctcRbase

Entry Detail

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General Information

Database ID: BRCA33522 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HOXB4 Full Name: homeobox B4 Category: mRNA Synonyms: HOX-2.6|HOX2|HOX2F Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 48575513 End Site(bp): 48580111 Gene Summary: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000182742 HGNC ID: HGNC:5115 Entrez Gene: 3214

Expression Profile of HOXB4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1-3p YES YES YES hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-320a YES YES YES hsa-miR-320b YES YES YES hsa-miR-320c YES YES YES hsa-miR-320d YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-377-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-613 YES YES YES hsa-miR-668-3p YES NO YES Display: