ctcRbase

Entry Detail

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General Information

Database ID: BRCA33759 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SULF1 Full Name: sulfatase 1 Category: mRNA Synonyms: SULF-1 Chromosome: chr8 Strand: + Coordinate: Start Site(bp): 69466624 End Site(bp): 69660915 Gene Summary: This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] External Links: Ensembl ID: ENSG00000137573 HGNC ID: HGNC:20391 Entrez Gene: 23213

Expression Profile of SULF1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-124-3p YES YES NO hsa-miR-1297 YES NO YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-137 YES YES YES hsa-miR-1-3p YES YES YES hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-182-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-205-5p YES YES YES hsa-miR-206 YES YES YES hsa-miR-208a-3p YES YES NO hsa-miR-208b-3p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES NO YES hsa-miR-214-3p YES YES NO hsa-miR-216a-5p YES YES NO hsa-miR-219a-2-3p YES NO YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-375 YES YES NO hsa-miR-376a-3p YES YES NO hsa-miR-376b-3p YES YES NO hsa-miR-378a-3p YES YES NO hsa-miR-384 YES YES NO hsa-miR-422a YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-499a-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-613 YES YES YES hsa-miR-93-5p YES YES YES Display: