ctcRbase

Entry Detail

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General Information

Database ID: BRCA34018 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: CRY2 Full Name: cryptochrome circadian regulator 2 Category: mRNA Synonyms: HCRY2|PHLL2 Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 45847118 End Site(bp): 45883248 Gene Summary: This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014] External Links: Ensembl ID: ENSG00000121671 HGNC ID: HGNC:2385 Entrez Gene: 1408

Expression Profile of CRY2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES YES hsa-let-7b-5p YES YES YES hsa-let-7c-5p YES YES YES hsa-let-7d-5p YES YES YES hsa-let-7e-5p YES YES YES hsa-let-7f-5p YES YES YES hsa-let-7g-5p YES YES YES hsa-let-7i-5p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-122-5p YES NO YES hsa-miR-142-5p YES NO YES hsa-miR-17-5p YES YES YES hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-216a-5p YES NO YES hsa-miR-216b-5p YES YES YES hsa-miR-24-3p YES NO YES hsa-miR-326 YES YES YES hsa-miR-329-3p YES YES NO hsa-miR-330-5p YES YES YES hsa-miR-340-5p YES NO YES hsa-miR-362-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-543 YES YES NO hsa-miR-7-5p YES YES YES hsa-miR-93-5p YES YES YES hsa-miR-98-5p YES YES YES Display: