Entry Detail



General Information

Database ID:BRCA34244
Cancer Type:breast cancer
Dataset:GSE111065
CTCs/CTM Isolation Method:microfluidics immunofluorescence



Gene Information

ncRNA Symbol:CBX2
Full Name:chromobox 2
Category:mRNA
Synonyms:CDCA6|M33|SRXY5
Chromosome:chr17
Strand:+
Coordinate:
Start Site(bp):79778132End Site(bp):79787983
Gene Summary:This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2010]
External Links:
Ensembl ID:ENSG00000173894
HGNC ID:HGNC:1552
Entrez Gene:84733



Expression Profile of CBX2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-let-7a-5p
YES
NO
YES
hsa-let-7b-5p
YES
NO
YES
hsa-let-7c-5p
YES
NO
YES
hsa-let-7d-5p
YES
NO
YES
hsa-let-7e-5p
YES
NO
YES
hsa-let-7f-5p
YES
NO
YES
hsa-let-7g-5p
YES
NO
YES
hsa-let-7i-5p
YES
NO
YES
hsa-miR-106a-5p
YES
YES
NO
hsa-miR-106b-5p
YES
YES
NO
hsa-miR-124-3p
YES
YES
YES
hsa-miR-1271-5p
YES
YES
NO
hsa-miR-15a-5p
NO
YES
YES
hsa-miR-15b-5p
NO
YES
YES
hsa-miR-16-5p
NO
YES
YES
hsa-miR-17-5p
YES
YES
NO
hsa-miR-182-5p
YES
NO
YES
hsa-miR-18a-5p
YES
YES
NO
hsa-miR-18b-5p
YES
YES
NO
hsa-miR-195-5p
NO
YES
YES
hsa-miR-20a-5p
YES
YES
NO
hsa-miR-20b-5p
YES
YES
NO
hsa-miR-219a-5p
YES
NO
YES
hsa-miR-23a-3p
YES
YES
NO
hsa-miR-23b-3p
YES
YES
NO
hsa-miR-30a-5p
YES
YES
YES
hsa-miR-30b-5p
YES
YES
YES
hsa-miR-30c-5p
YES
YES
YES
hsa-miR-30d-5p
YES
YES
YES
hsa-miR-30e-5p
YES
YES
YES
hsa-miR-326
YES
YES
NO
hsa-miR-330-5p
YES
YES
NO
hsa-miR-424-5p
NO
YES
YES
hsa-miR-497-5p
NO
YES
YES
hsa-miR-506-3p
YES
YES
NO
hsa-miR-93-5p
YES
YES
NO
hsa-miR-96-5p
YES
YES
NO
hsa-miR-98-5p
YES
NO
YES
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