ctcRbase

Entry Detail

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General Information

Database ID: BRCA34391 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: HOXC4 Full Name: homeobox C4 Category: mRNA Synonyms: HOX3|HOX3E|cp19 Chromosome: chr12 Strand: + Coordinate: Start Site(bp): 54016931 End Site(bp): 54056030 Gene Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000198353 HGNC ID: HGNC:5126 Entrez Gene: 3221

Expression Profile of HOXC4 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-129-5p YES YES NO hsa-miR-1297 YES YES NO hsa-miR-137 YES YES YES hsa-miR-185-5p YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-25-3p YES YES YES hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-410-3p YES YES NO hsa-miR-455-3p YES NO YES hsa-miR-491-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES Display: