ctcRbase

Entry Detail

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General Information

Database ID: BRCA34634 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SLC12A5 Full Name: solute carrier family 12 member 5 Category: mRNA Synonyms: EIEE34|EIG14|KCC2|hKCC2 Chromosome: chr20 Strand: + Coordinate: Start Site(bp): 46021690 End Site(bp): 46060152 Gene Summary: K-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2008] External Links: Ensembl ID: ENSG00000124140 HGNC ID: HGNC:13818 Entrez Gene: 57468

Expression Profile of SLC12A5 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-130a-3p YES YES YES hsa-miR-130b-3p YES YES YES hsa-miR-139-5p YES YES NO hsa-miR-181a-5p YES YES YES hsa-miR-181b-5p YES YES YES hsa-miR-181c-5p YES YES YES hsa-miR-181d-5p YES YES YES hsa-miR-191-5p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-224-5p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-301a-3p YES YES YES hsa-miR-301b-3p YES YES YES hsa-miR-32-5p YES YES YES hsa-miR-33a-5p YES YES YES hsa-miR-33b-5p YES YES YES hsa-miR-340-5p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-369-3p YES NO NO hsa-miR-371a-5p YES YES NO hsa-miR-376c-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-454-3p YES YES YES hsa-miR-494-3p YES YES NO hsa-miR-543 YES YES YES hsa-miR-874-3p YES YES YES hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-9-5p YES YES NO hsa-miR-96-5p YES YES YES Display: