ctcRbase

Entry Detail

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General Information

Database ID: BRCA34745 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: MAP2K7 Full Name: mitogen-activated protein kinase kinase 7 Category: mRNA Synonyms: JNKK2|MAPKK7|MEK|MEK 7|MKK7|PRKMK7|SAPKK-4|SAPKK4 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 7903843 End Site(bp): 7914478 Gene Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] External Links: Ensembl ID: ENSG00000076984 HGNC ID: HGNC:6847 Entrez Gene: 5609

Expression Profile of MAP2K7 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-138-5p YES NO YES hsa-miR-141-3p YES YES YES hsa-miR-200a-3p YES YES YES hsa-miR-27a-3p YES YES YES hsa-miR-27b-3p YES YES YES hsa-miR-331-3p YES NO YES hsa-miR-370-3p YES YES YES hsa-miR-421 YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-493-3p YES NO YES hsa-miR-505-3p YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-9-5p YES NO YES Display: