Entry Detail



General Information

Database ID:BRCA35051
Cancer Type:breast cancer
Dataset:GSE41245
CTCs/CTM Isolation Method:CTC-Chip



Gene Information

ncRNA Symbol:RHOBTB2
Full Name:Rho related BTB domain containing 2
Category:mRNA
Synonyms:DBC2|EIEE64
Chromosome:chr8
Strand:+
Coordinate:
Start Site(bp):22987417End Site(bp):23020199
Gene Summary:The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
External Links:
Ensembl ID:ENSG00000008853
HGNC ID:HGNC:18756
Entrez Gene:23221



Expression Profile of RHOBTB2 Gene

 







Regulatory Relationship

mRNA targets:NA
miRNA targets:
miRNA NamePITAmiRandaRNAhybrid
hsa-miR-129-5p
YES
YES
YES
hsa-miR-149-5p
YES
NO
YES
hsa-miR-15a-5p
YES
YES
YES
hsa-miR-15b-5p
YES
YES
YES
hsa-miR-16-5p
YES
YES
YES
hsa-miR-195-5p
YES
YES
YES
hsa-miR-214-3p
YES
YES
NO
hsa-miR-326
YES
NO
YES
hsa-miR-330-5p
YES
NO
YES
hsa-miR-410-3p
YES
NO
YES
hsa-miR-424-5p
YES
YES
YES
hsa-miR-497-5p
YES
YES
YES
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