ctcRbase

Entry Detail

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General Information

Database ID: BRCA35320 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ABCC1 Full Name: ATP binding cassette subfamily C member 1 Category: mRNA Synonyms: ABC29|ABCC|GS-X|MRP|MRP1 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 15949577 End Site(bp): 16143074 Gene Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012] External Links: Ensembl ID: ENSG00000103222 HGNC ID: HGNC:51 Entrez Gene: 4363

Expression Profile of ABCC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-133a-3p YES NO YES hsa-miR-133b YES NO YES hsa-miR-141-3p YES YES NO hsa-miR-145-5p YES NO YES hsa-miR-185-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-199b-5p YES YES YES hsa-miR-200a-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-217 YES NO YES hsa-miR-224-5p YES NO YES hsa-miR-326 YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-379-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-653-5p YES YES NO hsa-miR-654-5p YES NO NO hsa-miR-7-5p YES YES YES hsa-miR-873-5p YES YES YES Display: