ctcRbase

Entry Detail

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General Information

Database ID: BRCA35851 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: FAM111B Full Name: family with sequence similarity 111 member B Category: mRNA Synonyms: CANP|POIKTMP Chromosome: chr11 Strand: + Coordinate: Start Site(bp): 59107185 End Site(bp): 59127410 Gene Summary: This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014] External Links: Ensembl ID: ENSG00000189057 HGNC ID: HGNC:24200 Entrez Gene: 374393

Expression Profile of FAM111B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-217 YES YES NO hsa-miR-23a-3p YES YES NO hsa-miR-23b-3p YES YES NO hsa-miR-599 YES YES NO Display: