ctcRbase

Entry Detail

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General Information

Database ID: BRCA36054 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: THBD Full Name: thrombomodulin Category: mRNA Synonyms: AHUS6|BDCA3|CD141|THPH12|THRM|TM Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 23045633 End Site(bp): 23049741 Gene Summary: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000178726 HGNC ID: HGNC:11784 Entrez Gene: 7056

Expression Profile of THBD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-141-3p YES YES NO hsa-miR-18a-5p YES YES YES hsa-miR-18b-5p YES YES YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200a-3p YES YES NO hsa-miR-21-5p YES NO YES hsa-miR-34a-5p YES YES NO hsa-miR-34c-5p YES YES NO hsa-miR-384 YES YES NO hsa-miR-449a YES YES NO hsa-miR-449b-5p YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-495-3p YES YES NO hsa-miR-590-5p YES NO YES hsa-miR-875-5p YES YES NO hsa-miR-876-5p YES YES NO Display: