ctcRbase

Entry Detail

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General Information

Database ID: BRCA36081 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: LDB2 Full Name: LIM domain binding 2 Category: mRNA Synonyms: CLIM1|LDB-2|LDB1 Chromosome: chr4 Strand: - Coordinate: Start Site(bp): 16501541 End Site(bp): 16898809 Gene Summary: The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015] External Links: Ensembl ID: ENSG00000169744 HGNC ID: HGNC:6533 Entrez Gene: 9079

Expression Profile of LDB2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-1271-5p YES YES YES hsa-miR-135a-5p YES YES YES hsa-miR-135b-5p YES YES YES hsa-miR-148a-3p YES YES NO hsa-miR-148b-3p YES YES NO hsa-miR-152-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-182-5p YES YES NO hsa-miR-329-3p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-361-5p YES YES NO hsa-miR-362-3p YES YES NO hsa-miR-421 YES YES NO hsa-miR-448 YES YES NO hsa-miR-96-5p YES YES YES Display: