ctcRbase

Entry Detail

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General Information

Database ID: BRCA36129 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: UVSSA Full Name: UV stimulated scaffold protein A Category: mRNA Synonyms: KIAA1530|UVSS3 Chromosome: chr4 Strand: + Coordinate: Start Site(bp): 1347266 End Site(bp): 1395992 Gene Summary: The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in this gene can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000163945 HGNC ID: HGNC:29304 Entrez Gene: 57654

Expression Profile of UVSSA Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-186-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-218-5p YES YES NO hsa-miR-299-3p YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-486-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-542-3p YES YES NO Display: