ctcRbase

Entry Detail

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General Information

Database ID: BRCA36173 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: MAP3K10 Full Name: mitogen-activated protein kinase kinase kinase 10 Category: mRNA Synonyms: MEKK10|MLK2|MST Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 40191744 End Site(bp): 40215575 Gene Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000130758 HGNC ID: HGNC:6849 Entrez Gene: 4294

Expression Profile of MAP3K10 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-125a-5p YES YES YES hsa-miR-125b-5p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-155-5p YES YES YES hsa-miR-181a-5p YES NO YES hsa-miR-181b-5p YES NO YES hsa-miR-181c-5p YES NO YES hsa-miR-181d-5p YES NO YES hsa-miR-221-3p YES YES NO hsa-miR-222-3p YES YES NO hsa-miR-339-5p YES YES YES hsa-miR-874-3p YES YES NO Display: