ctcRbase

Entry Detail

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General Information

Database ID: BRCA36337 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: JAG1 Full Name: jagged 1 Category: mRNA Synonyms: AGS|AGS1|AHD|AWS|CD339|DCHE|HJ1|JAGL1 Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 10637684 End Site(bp): 10674107 Gene Summary: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000101384 HGNC ID: HGNC:6188 Entrez Gene: 182

Expression Profile of JAG1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-128-3p YES YES YES hsa-miR-129-5p YES YES NO hsa-miR-1297 YES NO YES hsa-miR-137 YES YES YES hsa-miR-1-3p YES YES NO hsa-miR-140-5p YES YES YES hsa-miR-141-3p YES YES YES hsa-miR-153-3p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-18a-5p YES YES NO hsa-miR-18b-5p YES YES NO hsa-miR-200a-3p YES YES YES hsa-miR-205-5p YES YES NO hsa-miR-206 YES YES NO hsa-miR-21-5p YES YES YES hsa-miR-218-5p YES YES YES hsa-miR-224-5p YES YES NO hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-26a-5p YES NO YES hsa-miR-26b-5p YES NO YES hsa-miR-300 YES YES NO hsa-miR-335-5p YES YES NO hsa-miR-33a-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-34a-5p YES YES YES hsa-miR-34c-5p YES YES YES hsa-miR-371a-5p YES YES NO hsa-miR-377-3p YES YES YES hsa-miR-378a-3p YES YES NO hsa-miR-381-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-422a YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-449a YES YES YES hsa-miR-449b-5p YES YES YES hsa-miR-489-3p YES NO YES hsa-miR-490-3p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-590-5p YES YES YES hsa-miR-613 YES YES NO hsa-miR-653-5p YES YES NO Display: