ctcRbase

Entry Detail

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General Information

Database ID: BRCA36741 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: SMAD6 Full Name: SMAD family member 6 Category: mRNA Synonyms: AOVD2|HsT17432|MADH6|MADH7 Chromosome: chr15 Strand: + Coordinate: Start Site(bp): 66702228 End Site(bp): 66782848 Gene Summary: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014] External Links: Ensembl ID: ENSG00000137834 HGNC ID: HGNC:6772 Entrez Gene: 4091

Expression Profile of SMAD6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-134-5p YES YES YES hsa-miR-136-5p YES YES NO hsa-miR-155-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-196a-5p YES YES YES hsa-miR-196b-5p YES YES YES hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-25-3p YES YES YES hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-32-5p YES YES YES hsa-miR-326 YES YES YES hsa-miR-329-3p YES YES YES hsa-miR-330-5p YES YES YES hsa-miR-340-5p YES YES NO hsa-miR-362-3p YES YES YES hsa-miR-363-3p YES YES YES hsa-miR-367-3p YES YES YES hsa-miR-369-3p YES NO YES hsa-miR-371a-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-374a-5p YES NO YES hsa-miR-374b-5p YES NO YES hsa-miR-379-5p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-429 YES YES NO hsa-miR-488-3p YES YES YES hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-7-5p YES YES NO hsa-miR-92a-3p YES YES YES hsa-miR-92b-3p YES YES YES hsa-miR-93-5p YES YES YES Display: