ctcRbase

Entry Detail

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General Information

Database ID: BRCA37480 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: PPARD Full Name: peroxisome proliferator activated receptor delta Category: mRNA Synonyms: FAAR|NR1C2|NUC1|NUCI|NUCII|PPARB Chromosome: chr6 Strand: + Coordinate: Start Site(bp): 35342558 End Site(bp): 35428191 Gene Summary: This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Aug 2017] External Links: Ensembl ID: ENSG00000112033 HGNC ID: HGNC:9235 Entrez Gene: 5467

Expression Profile of PPARD Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES NO YES hsa-miR-106b-5p YES NO YES hsa-miR-138-5p YES YES YES hsa-miR-148a-3p YES NO YES hsa-miR-148b-3p YES NO YES hsa-miR-152-3p YES NO YES hsa-miR-17-5p YES NO YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-20a-5p YES NO YES hsa-miR-20b-5p YES NO YES hsa-miR-223-3p YES YES NO hsa-miR-24-3p YES YES NO hsa-miR-29a-3p YES NO YES hsa-miR-29b-3p YES NO YES hsa-miR-29c-3p YES NO YES hsa-miR-519d-3p YES NO YES hsa-miR-520f-3p YES NO YES hsa-miR-93-5p YES NO YES hsa-miR-9-5p YES NO YES Display: