| ncRNA Symbol: | IRAK3 |
| Full Name: | interleukin 1 receptor associated kinase 3 |
| Category: | mRNA |
| Synonyms: | ASRT5|IRAKM |
| Chromosome: | chr12 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 66188879 | End Site(bp): | 66254622 |
|
| Gene Summary: | This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| External Links: | |