ctcRbase

Entry Detail

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General Information

Database ID: BRCA37535 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: BGN Full Name: biglycan Category: mRNA Synonyms: DSPG1|MRLS|PG-S1|PGI|SEMDX|SLRR1A Chromosome: chrX Strand: + Coordinate: Start Site(bp): 153494939 End Site(bp): 153509554 Gene Summary: This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in bone growth, muscle development and regeneration, and collagen fibril assembly in multiple tissues. This protein may also regulate inflammation and innate immunity. Additionally, the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients. This gene and the related gene decorin are thought to be the result of a gene duplication. [provided by RefSeq, Nov 2015] External Links: Ensembl ID: ENSG00000182492 HGNC ID: HGNC:1044 Entrez Gene: 633

Expression Profile of BGN Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-185-5p YES YES NO hsa-miR-296-3p YES YES NO hsa-miR-326 YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-330-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-488-3p YES YES NO Display: