ctcRbase

Entry Detail

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General Information

Database ID: BRCA37627 Cancer Type: breast cancer Dataset: GSE111065 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: DVL1 Full Name: dishevelled segment polarity protein 1 Category: mRNA Synonyms: DRS2|DVL|DVL1L1|DVL1P1 Chromosome: chr1 Strand: - Coordinate: Start Site(bp): 1335276 End Site(bp): 1349350 Gene Summary: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000107404 HGNC ID: HGNC:3084 Entrez Gene: 1855

Expression Profile of DVL1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES NO NO hsa-miR-107 YES NO NO hsa-miR-139-5p YES NO YES hsa-miR-144-3p YES YES YES hsa-miR-15a-5p YES YES NO hsa-miR-15b-5p YES YES NO hsa-miR-16-5p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-195-5p YES YES NO hsa-miR-424-5p YES YES NO hsa-miR-497-5p YES YES NO hsa-miR-503-5p YES YES NO Display: