ctcRbase

Entry Detail

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General Information

Database ID: BRCA37817 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: KMT2B Full Name: lysine methyltransferase 2B Category: mRNA Synonyms: CXXC10|DYT28|HRX2|MLL1B|MLL2|MLL4|TRX2|WBP-7|WBP7 Chromosome: chr19 Strand: + Coordinate: Start Site(bp): 35718019 End Site(bp): 35738878 Gene Summary: This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000272333 HGNC ID: HGNC:15840 Entrez Gene: 9757

Expression Profile of KMT2B Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-153-3p YES YES YES hsa-miR-17-5p YES YES YES hsa-miR-186-5p YES YES NO hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-296-5p YES NO YES hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-448 YES YES NO hsa-miR-454-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-876-5p YES YES NO hsa-miR-93-5p YES YES YES Display: