ctcRbase

Entry Detail

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General Information

Database ID: BRCA38172 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: CELSR2 Full Name: cadherin EGF LAG seven-pass G-type receptor 2 Category: mRNA Synonyms: ADGRC2|CDHF10|EGFL2|Flamingo1|MEGF3 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 109250019 End Site(bp): 109275750 Gene Summary: The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000143126 HGNC ID: HGNC:3231 Entrez Gene: 1952

Expression Profile of CELSR2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-103a-3p YES YES YES hsa-miR-106a-5p YES YES YES hsa-miR-106b-5p YES YES YES hsa-miR-107 YES YES YES hsa-miR-125a-5p YES NO YES hsa-miR-125b-5p YES NO YES hsa-miR-1271-5p YES YES YES hsa-miR-1297 YES YES NO hsa-miR-145-5p YES YES NO hsa-miR-17-5p YES YES YES hsa-miR-193a-3p YES YES YES hsa-miR-193b-3p YES YES YES hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-20a-5p YES YES YES hsa-miR-20b-5p YES YES YES hsa-miR-214-3p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-26a-5p YES YES NO hsa-miR-26b-5p YES YES NO hsa-miR-328-3p YES NO YES hsa-miR-338-3p YES YES YES hsa-miR-423-5p YES NO YES hsa-miR-431-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-491-5p YES YES NO hsa-miR-495-3p YES YES NO hsa-miR-519d-3p YES YES YES hsa-miR-615-3p YES YES NO hsa-miR-93-5p YES YES YES hsa-miR-96-5p YES YES YES Display: