ctcRbase

Entry Detail

---



General Information

Database ID: BRCA38535 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: PLCD3 Full Name: phospholipase C delta 3 Category: mRNA Synonyms: PLC-delta-3 Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 45108967 End Site(bp): 45133354 Gene Summary: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000161714 HGNC ID: HGNC:9061 Entrez Gene: 113026

Expression Profile of PLCD3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-10a-5p YES YES NO hsa-miR-10b-5p YES YES NO hsa-miR-224-5p YES YES NO hsa-miR-25-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-339-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-485-5p YES NO YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: