ctcRbase

Entry Detail

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General Information

Database ID: BRCA38985 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: DISC1 Full Name: DISC1 scaffold protein Category: mRNA Synonyms: C1orf136|SCZD9 Chromosome: chr1 Strand: + Coordinate: Start Site(bp): 231626815 End Site(bp): 232041272 Gene Summary: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000162946 HGNC ID: HGNC:2888 Entrez Gene: 27185

Expression Profile of DISC1 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-143-3p YES YES NO hsa-miR-185-5p YES YES NO hsa-miR-192-5p YES YES NO hsa-miR-215-5p YES YES NO hsa-miR-346 YES YES NO hsa-miR-7-5p YES YES NO Display: