ctcRbase

Entry Detail

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General Information

Database ID: BRCA39303 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: NFATC2 Full Name: nuclear factor of activated T cells 2 Category: mRNA Synonyms: NFAT1|NFATP Chromosome: chr20 Strand: - Coordinate: Start Site(bp): 51386957 End Site(bp): 51562831 Gene Summary: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012] External Links: Ensembl ID: ENSG00000101096 HGNC ID: HGNC:7776 Entrez Gene: 4773

Expression Profile of NFATC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-135a-5p YES YES NO hsa-miR-135b-5p YES YES NO hsa-miR-143-3p YES YES YES hsa-miR-424-5p NO NO YES hsa-miR-431-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-497-5p NO NO YES Display: