| ncRNA Symbol: | PRICKLE1 |
| Full Name: | prickle planar cell polarity protein 1 |
| Category: | mRNA |
| Synonyms: | EPM1B|RILP |
| Chromosome: | chr12 |
| Strand: | - |
| Coordinate: | | Start Site(bp): | 42456757 | End Site(bp): | 42590355 |
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| Gene Summary: | This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009] |
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