ctcRbase

Entry Detail

---



General Information

Database ID: BRCA40044 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: ROBO2 Full Name: roundabout guidance receptor 2 Category: mRNA Synonyms: SAX3 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 75906695 End Site(bp): 77649964 Gene Summary: The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] External Links: Ensembl ID: ENSG00000185008 HGNC ID: HGNC:10250 Entrez Gene: 6092

Expression Profile of ROBO2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-140-3p YES NO YES hsa-miR-183-5p YES YES YES hsa-miR-197-3p YES YES NO hsa-miR-218-5p YES YES YES hsa-miR-23a-3p YES YES YES hsa-miR-23b-3p YES YES YES hsa-miR-25-3p YES YES NO hsa-miR-32-5p YES YES NO hsa-miR-363-3p YES YES NO hsa-miR-367-3p YES YES NO hsa-miR-375 YES YES NO hsa-miR-411-5p YES YES NO hsa-miR-433-3p YES YES NO hsa-miR-452-5p YES NO YES hsa-miR-582-5p YES NO YES hsa-miR-92a-3p YES YES NO hsa-miR-92b-3p YES YES NO Display: