ctcRbase

Entry Detail

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General Information

Database ID: BRCA40446 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: ARHGEF6 Full Name: Rac/Cdc42 guanine nucleotide exchange factor 6 Category: mRNA Synonyms: COOL2|Cool-2|MRX46|PIXA|alpha-PIX|alphaPIX Chromosome: chrX Strand: - Coordinate: Start Site(bp): 136665547 End Site(bp): 136782088 Gene Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000129675 HGNC ID: HGNC:685 Entrez Gene: 9459

Expression Profile of ARHGEF6 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-320a YES YES NO hsa-miR-320b YES YES NO hsa-miR-320c YES YES NO hsa-miR-320d YES YES NO hsa-miR-340-5p YES YES NO Display: