| ncRNA Symbol: | OSCAR | | Full Name: | osteoclast associated, immunoglobulin-like receptor | | Category: | mRNA | | Synonyms: | PIGR3|PIgR-3 | | Chromosome: | chr19 | | Strand: | - | | Coordinate: | | Start Site(bp): | 54094668 | End Site(bp): | 54102692 | | | Gene Summary: | Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013] | | External Links: | |
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