ctcRbase

Entry Detail

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General Information

Database ID: BRCA41721 Cancer Type: breast cancer Dataset: GSE109761 CTCs/CTM Isolation Method: microfluidics immunofluorescence

Gene Information

ncRNA Symbol: SHPK Full Name: sedoheptulokinase Category: mRNA Synonyms: CARKL|SHK Chromosome: chr17 Strand: - Coordinate: Start Site(bp): 3608262 End Site(bp): 3636322 Gene Summary: The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000197417 HGNC ID: HGNC:1492 Entrez Gene: 23729

Expression Profile of SHPK Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-124-3p YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-206 YES YES NO hsa-miR-324-5p YES NO YES hsa-miR-326 YES YES NO hsa-miR-330-5p YES YES NO hsa-miR-340-5p YES YES NO hsa-miR-370-3p YES NO YES hsa-miR-485-5p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-613 YES YES NO Display: