ctcRbase

Entry Detail

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General Information

Database ID: BRCA41767 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: STC2 Full Name: stanniocalcin 2 Category: mRNA Synonyms: STC-2|STCRP Chromosome: chr5 Strand: - Coordinate: Start Site(bp): 173314713 End Site(bp): 173329503 Gene Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000113739 HGNC ID: HGNC:11374 Entrez Gene: 8614

Expression Profile of STC2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-125a-5p YES YES NO hsa-miR-125b-5p YES YES NO hsa-miR-1271-5p YES NO YES hsa-miR-133a-3p YES YES NO hsa-miR-133b YES YES NO hsa-miR-137 YES YES NO hsa-miR-1-3p YES YES YES hsa-miR-140-5p YES YES YES hsa-miR-17-5p YES YES NO hsa-miR-181a-5p YES YES NO hsa-miR-181b-5p YES YES NO hsa-miR-181c-5p YES YES NO hsa-miR-181d-5p YES YES NO hsa-miR-184 YES NO YES hsa-miR-190a-5p YES YES NO hsa-miR-190b YES YES NO hsa-miR-199a-3p YES NO YES hsa-miR-199b-3p YES NO YES hsa-miR-19a-3p YES YES NO hsa-miR-19b-3p YES YES NO hsa-miR-200b-3p YES YES NO hsa-miR-200c-3p YES YES NO hsa-miR-204-5p YES YES NO hsa-miR-206 YES YES YES hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-24-3p YES YES YES hsa-miR-326 YES YES NO hsa-miR-328-3p YES YES NO hsa-miR-329-3p YES NO NO hsa-miR-330-5p YES YES NO hsa-miR-362-3p YES NO NO hsa-miR-376c-3p YES YES NO hsa-miR-410-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-429 YES YES NO hsa-miR-489-3p YES NO YES hsa-miR-519d-3p YES YES NO hsa-miR-532-5p YES NO YES hsa-miR-542-3p YES NO YES hsa-miR-613 YES YES YES hsa-miR-625-5p YES NO NO hsa-miR-873-5p YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-96-5p YES NO YES Display: