ctcRbase

Entry Detail

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General Information

Database ID: BRCA41775 Cancer Type: breast cancer Dataset: GSE41245 CTCs/CTM Isolation Method: CTC-Chip

Gene Information

ncRNA Symbol: JPH3 Full Name: junctophilin 3 Category: mRNA Synonyms: CAGL237|HDL2|JP-3|JP3|TNRC22 Chromosome: chr16 Strand: + Coordinate: Start Site(bp): 87601835 End Site(bp): 87698156 Gene Summary: Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. CAG/CTG repeat expansion from normally 6-28 repeats to 40-59 repeats in the 3' UTR of this gene have been associated with Huntington disease-like 2 (HDL2). This gene is a member of the junctophilin gene family. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2016] External Links: Ensembl ID: ENSG00000154118 HGNC ID: HGNC:14203 Entrez Gene: 57338

Expression Profile of JPH3 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-129-5p YES YES YES hsa-miR-130a-3p YES YES NO hsa-miR-130b-3p YES YES NO hsa-miR-139-5p YES YES NO hsa-miR-148a-3p YES YES YES hsa-miR-148b-3p YES YES YES hsa-miR-152-3p YES YES YES hsa-miR-186-5p YES YES YES hsa-miR-196a-5p YES YES NO hsa-miR-196b-5p YES YES NO hsa-miR-199a-5p YES YES YES hsa-miR-204-5p YES YES NO hsa-miR-211-5p YES YES NO hsa-miR-301a-3p YES YES NO hsa-miR-301b-3p YES YES NO hsa-miR-323a-3p YES NO YES hsa-miR-330-3p YES NO YES hsa-miR-448 YES YES YES hsa-miR-454-3p YES YES NO Display: