| ncRNA Symbol: | IRGM |
| Full Name: | immunity related GTPase M |
| Category: | mRNA |
| Synonyms: | IFI1|IRGM1|LRG-47|LRG47 |
| Chromosome: | chr5 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 150846523 | End Site(bp): | 150900736 |
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| Gene Summary: | This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016] |
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