ctcRbase

Entry Detail

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General Information

Database ID: BRCA42332 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: SOX2 Full Name: SRY-box 2 Category: mRNA Synonyms: ANOP3|MCOPS3 Chromosome: chr3 Strand: + Coordinate: Start Site(bp): 181711924 End Site(bp): 181714436 Gene Summary: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008] External Links: Ensembl ID: ENSG00000181449 HGNC ID: HGNC:11195 Entrez Gene: 6657

Expression Profile of SOX2 Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-miR-101-3p YES YES NO hsa-miR-128-3p YES YES NO hsa-miR-129-5p YES YES NO hsa-miR-144-3p YES YES NO hsa-miR-153-3p YES YES NO hsa-miR-371a-5p YES YES YES hsa-miR-382-5p YES YES NO hsa-miR-448 YES YES NO Display: