ctcRbase

Entry Detail

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General Information

Database ID: BRCA42559 Cancer Type: breast cancer Dataset: GSE55807 CTCs/CTM Isolation Method: CTC-iChip

Gene Information

ncRNA Symbol: FAM57A Full Name: family with sequence similarity 57 member A Category: mRNA Synonyms: CT120 Chromosome: chr17 Strand: + Coordinate: Start Site(bp): 732412 End Site(bp): 742972 Gene Summary: The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] External Links: Ensembl ID: ENSG00000167695 HGNC ID: HGNC:29646 Entrez Gene: 79850

Expression Profile of FAM57A Gene

 

Regulatory Relationship

mRNA targets: NA miRNA targets: miRNA Name PITA miRanda RNAhybrid hsa-let-7a-5p YES YES NO hsa-let-7b-5p YES YES NO hsa-let-7c-5p YES YES NO hsa-let-7d-5p YES YES NO hsa-let-7e-5p YES YES NO hsa-let-7f-5p YES YES NO hsa-let-7g-5p YES YES NO hsa-let-7i-5p YES YES NO hsa-miR-106a-5p YES YES NO hsa-miR-106b-5p YES YES NO hsa-miR-124-3p YES YES NO hsa-miR-1271-5p YES YES NO hsa-miR-133a-3p YES YES YES hsa-miR-133b YES YES YES hsa-miR-134-5p YES YES NO hsa-miR-1-3p YES YES NO hsa-miR-17-5p YES YES NO hsa-miR-20a-5p YES YES NO hsa-miR-20b-5p YES YES NO hsa-miR-302a-3p YES YES NO hsa-miR-302b-3p YES YES NO hsa-miR-302c-3p YES YES NO hsa-miR-302d-3p YES YES NO hsa-miR-302e YES YES NO hsa-miR-31-5p YES YES NO hsa-miR-372-3p YES YES NO hsa-miR-373-3p YES YES NO hsa-miR-425-5p YES YES NO hsa-miR-485-5p YES YES NO hsa-miR-488-3p YES YES NO hsa-miR-506-3p YES YES NO hsa-miR-519d-3p YES YES NO hsa-miR-520a-3p YES YES NO hsa-miR-520b YES YES NO hsa-miR-520c-3p YES YES NO hsa-miR-520d-3p YES YES NO hsa-miR-520e YES YES NO hsa-miR-93-5p YES YES NO hsa-miR-96-5p YES YES NO hsa-miR-98-5p YES YES NO Display: