| ncRNA Symbol: | AKR1C1 |
| Full Name: | aldo-keto reductase family 1 member C1 |
| Category: | mRNA |
| Synonyms: | 2-ALPHA-HSD|20-ALPHA-HSD|C9|DD1|DD1/DD2|DDH|DDH1|H-37|HAKRC|HBAB|MBAB |
| Chromosome: | chr10 |
| Strand: | + |
| Coordinate: | | Start Site(bp): | 4963253 | End Site(bp): | 4983283 |
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| Gene Summary: | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008] |
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